Accokeek (), "at the edge of the hill" in Algonquin, is a census-designated place (CDP) located in Prince George's County, Maryland, United States. The CDP is located on the Potomac River, borders Charles County and is approximately 17 miles from Washington. It is a part of the Washington metropolitan area. The population of the CDP, as of the 2010 United States Census was 10,573, making it the 118th most populous place in the state of Maryland.
While the area around Accokeek was occupied by Native Americans since approximately 2,000 BCE, John Smith was the first European to settle the area in 1608. In 1990, the United States Census Bureau officially made Accokeek a CDP.
The area around Accokeek had been occupied since around 2000 BC; however, the first permanent village was established in c. 1200 AD by the Piscataway tribe. Captain John Smith was the first European to see the Accokeek area. In 1608, he sailed the Potomac River and found the Moyaone village. At the time of the discovery, Moyaone was the seat of government for the Piscataway Tribe.