Depoe Bay is a city in Lincoln County, Oregon, United States, located on U.S. Route 101 next to the Pacific Ocean. The population was 1,398 at the 2010 census. The bay of the same name is a 6-acre (2.4 ha) harbor that the city promotes as the world's smallest navigable harbor.
Depoe Bay was named for Siletz Indian Charles "Charley" Depot who was originally allotted the land in 1894 as part of the Dawes Act of 1887. There are conflicting accounts of the origin of his name. One says he was given the name "Depot Charley" for working at the military depot near Toledo, Oregon. The family was later known as "DePoe". His original tribal affiliation was Tututni.
In 1975, the fishing trip sequence in One Flew Over the Cuckoo's Nest was filmed in Depoe Bay.
In 2008, restaurant scenes from The Burning Plain were filmed in Depoe Bay, at the Tidal Raves restaurant.
On March 11, 2011, Depoe Bay's port was damaged by a tsunami caused by the Tōhoku earthquake off the coast of Japan.
On August 21, 2017, Depoe Bay became one of the first places in the United States to witness totality of the solar eclipse.
According to the United States Census Bureau, the city has a total area of 1.81 square miles (4.69 km2), all of it land.
As of the census of 2010, there were 1,398 people, 714 households, and 411 families living in the city. The population density was 772.4 inhabitants per square mile (298.2/km2). There were 1,158 housing units at an average density of 639.8 per square mile (247.0/km2).