Millersburg is a home rule-class city in Bourbon County, Kentucky, United States. The population was 792 at the 2010 census. It is part of the Lexington–Fayette Metropolitan Statistical Area.
Millersburg was founded in 1817. It was named for John Miller.
Millersburg is located in northeastern Bourbon County at 38°18′12″N 84°08′46″W, reaching to the Nicholas County border. U.S. Route 68 (Main Street) passes through the center of town, leading southwest 9 miles (14 km) to Paris, the county seat, and 29 miles (47 km) to Lexington. It is 37 miles (60 km) northeast to Maysville on the Ohio River.
According to the United States Census Bureau, Millersburg has a total area of 0.42 square miles (1.1 km2), all land.
As of the census of 2000, there were 842 people, 356 households, and 248 families residing in the city. The population density was 2,432.5 people per square mile (928.9/km²). There were 390 housing units at an average density of 1,126.7 per square mile (430.2/km²).