Ramona is a town in Lake County, South Dakota, United States. The population was 174 at the 2010 census.
Ramona was laid out in 1886, and named for the local Ramon family.
Ramona is located at 44°7′12″N 97°13′5″W (44.120055, -97.217981).
According to the United States Census Bureau, the town has a total area of 0.27 square miles (0.70 km2), all land.
Ramona has been assigned the ZIP code 57054 and the FIPS place code 52860.
As of the census of 2010, there were 174 people, 81 households, and 48 families residing in the town. The population density was 644.4 inhabitants per square mile (248.8/km2). There were 112 housing units at an average density of 414.8 per square mile (160.2/km2). The racial makeup of the town was 94.3% White, 1.7% Native American, 1.1% Asian, 1.1% from other races, and 1.7% from two or more races. Hispanic or Latino of any race were 3.4% of the population.
There were 81 households, of which 24.7% had children under the age of 18 living with them, 48.1% were married couples living together, 8.6% had a female householder with no husband present, 2.5% had a male householder with no wife present, and 40.7% were non-families. 38.3% of all households were made up of individuals, and 29.6% had someone living alone who was 65 years of age or older.