Barstow is a city in San Bernardino County, California, United States. The population was 22,639 at the 2010 census. Barstow is located 67 miles (108 km) north of San Bernardino.
Barstow is a major transportation hub for the Inland Empire. Several major highways including Interstate 15, Interstate 40, and California State Route 58 converge in the city. It is the site of a large rail classification yard, belonging to the BNSF Railway. The Union Pacific Railroad also runs through town using trackage rights on BNSF's main line to Daggett 10 miles (16 km) east, from where it heads to Salt Lake City and the BNSF heads to Chicago.
Barstow is home to Marine Corps Logistics Base Barstow.
The settlement of Barstow began in the late 1830s in the Mormon Corridor. Every fall and winter, as the weather cooled, the rain produced new grass growth and replenished the water sources in the Mojave Desert.