Cleghorn is a city in Cherokee County, Iowa, United States. The population was 240 at the 2010 census.
Cleghorn is located at 42°48′46″N 95°42′43″W (42.812680, -95.711997).
According to the United States Census Bureau, the city has a total area of 0.34 square miles (0.88 km2), all land.
As of the census of 2010, there were 240 people, 106 households, and 71 families living in the city. The population density was 705.9 inhabitants per square mile (272.5/km2). There were 113 housing units at an average density of 332.4 per square mile (128.3/km2). The racial makeup of the city was 95.0% White, 0.8% African American, 0.4% Asian, and 3.8% from two or more races. Hispanic or Latino of any race were 3.8% of the population.
There were 106 households, of which 22.6% had children under the age of 18 living with them, 54.7% were married couples living together, 7.5% had a female householder with no husband present, 4.7% had a male householder with no wife present, and 33.0% were non-families. 29.2% of all households were made up of individuals, and 17% had someone living alone who was 65 years of age or older. The average household size was 2.26 and the average family size was 2.75.