Enola is a census-designated place (CDP) located along the Susquehanna River in East Pennsboro Township, Cumberland County, Pennsylvania, United States. The population was 6,111 at the 2010 census. Norfolk Southern operates Enola Yard, a large rail yard and locomotive shop in Enola. It is situated in Cumberland County, directly across the Susquehanna River from Harrisburg and is part of the Harrisburg–Carlisle Metropolitan Statistical Area.
The town came into existence due to the building of rail lines through the area. Local farmers Francis and Wesley Miller sold 2 acres (0.81 ha) to the Pennsylvania Railroad to be used as a flag station. Mr. Miller was given the honor of naming the train station. He named the station "Enola", after his daughter. Miller at the time was the only resident living in the area.