Hampton is an unincorporated community in Carter County, Tennessee, United States. Located a few miles southeast of Elizabethton and northwest of Roan Mountain, Hampton is surrounded on all sides by the Unaka Mountains. It is part of the Johnson City Metropolitan Statistical Area, which is a component of the Johnson City–Kingsport–Bristol, TN-VA Combined Statistical Area – commonly known as the "Tri-Cities" region.
Hampton was established in the late 1860s by Elijah Simerly, a state legislator and president of the East Tennessee and Western North Carolina Railroad. He named the community for his wife, Mary Hampton. Simerly built an elaborate, Italianate-style house which still stands at the corner of Main Street and 1st Avenue, and is listed on the National Register of Historic Places. The house is now known as the "Butler Mansion" after a later owner, Ralph Butler.
The Laurel Fork Railway served a mill in Hampton.
Hampton lies in a broad valley concentrated around the Doe River and its junction with two of its tributaries, namely the Little Doe River, which enters the area from the southwest, and Laurel Fork, which enters the area from the east. This valley is surrounded by Jenkins Mountain on the west, the Iron Mountains on the north, Pond Mountain to the east, and Cedar Mountain to the south. Just southeast of Hampton, the Doe River emerges from the Doe River Gorge, a narrow valley between Cedar Mountain and Fork Mountain.