Hartville is a city in Wright County, Missouri, United States. The population was 613 at the 2010 census. It is the county seat of Wright County.
A post office called Hartville has been in operation since 1842. The community bears the name of Isaac Hart, a pioneer citizen.
Much of the town was destroyed during the Battle of Hartville in 1863. John Wimer, who had served two nonconsecutive terms as mayor of St. Louis, sided with the Confederacy, even though he was opposed to slavery. Lt. Col. Wimer was killed in the battle and was buried at Hartville.
The Grovespring Tornado in 1959 destroyed most of Hartville's business district, including the post office. There were no major injuries since a warning alarm had given time to take cover.
Kelton House was listed on the National Register of Historic Places in 1983.
Hartville is located on Missouri routes 5 and 38, along the Wood's Fork of the Gasconade River which flows into the Gasconade just east of the community.