Holbrook (Navajo: Tʼiisyaakin) is a city in Navajo County, Arizona, United States. According to the 2010 census, the population of the city was 5,053. The city is the county seat of Navajo County.
Holbrook was founded in 1881 or 1882, when the railroad was built, and named to honor the first chief engineer of the Atlantic and Pacific Railroad, Henry Randolph Holbrook.
The Holbrook area was inhabited first by the Anasazi, then Puebloans, then the Navajo and Apache. In 1540 (some seventy years before Jamestown or the Pilgrims) Coronado searched for the Seven Cities of Cibola and camped some 60 miles east of Holbrook. Coronado sent an expedition west to find the Colorado River, and they crossed the Little Colorado some twenty-five miles east of Holbrook and found a wonderland of colors they named "El Desierto Pintada" - The Painted Desert. The expedition was then led by the Hopis to the Grand Canyon.
After the Mexican–American War ended in 1848 the area was ceded to the United States. From 1851-57 the U.S. Army sent three expeditions along the 35th parallel, the third led by Lt. Beale who created a ten foot wide wagon road. The area was known as Navajo Springs, after a spring a dozen miles northeast of Holbrook.