Jackson is a city in Clarke County, Alabama, United States. The population was 5,228 at the 2010 census. It was one of three wet settlements in an otherwise-dry county.
Jackson is located along the western border of Clarke County at coordinates 31.521°N 87.891°W / 31.521; -87.891, on a rise overlooking east bank of the Tombigbee River. According to the U.S. Census Bureau, the city has a total area of 15.8 square miles (41.0 km2), of which 15.6 square miles (40.5 km2) is land and 0.19 square miles (0.5 km2), or 1.21%, is water.
Jackson sits across the Tombigbee River from Washington County, Alabama.
At the 2010 census there were 5,228 people, 2,112 households, and 1,446 families living in the city. The population density was 334 people per square mile (129.1/km2). There were 2,426 housing units at an average density of 153.5 per square mile (59.1/km2). The racial makeup of the city was 54.9% White, 42.9% African American, 0.7% Native American, 0.4% Asian, 0.3% from other races, and 0.8% from two or more races. Hispanic or Latino of any race were 1.4%.
Of the 2,112 households 28.4% had children under the age of 18 living with them, 46.6% were married couples living together, 17.9% had a female householder with no husband present, and 31.5% were non-families. 29.4% of households were one person and 10.8% were one person aged 65 or older.