Jeffersonville is a village in the town of Cambridge, Vermont, United States. The population was 729 at the 2010 census, up from 568 at the 2000 census.
The village was originally called Cambridge Center. The name was changed to Jeffersonville in 1827 to honor Thomas Jefferson. The village was incorporated in 1897.
According to the United States Census Bureau, the village has a total area of 0.81 square miles (2.1 km2), of which 0.03 square miles (0.07 km2), or 3.25%, is water. The village is located near the geographic center of the town of Cambridge, along the south bank of the Lamoille River where it is joined by the Brewster River. Jeffersonville is 25 miles North-east of the city of Burlington, Vermont. Jeffersonville sits at 1,060 feet above sea level, surrounded by higher standing mountains, such as Mount Mansfield (the highest peak in Vermont at 4,393 feet [1,339m])), 4 miles to the east.
Jeffersonville has a humid continental climate (Köppen Dfb), with very cold winters and warm, humid summers. The monthly daily average temperatures ranges from 12 °F (−11.1 °C) in January to 64.4 °F (18 °C) in July.