Moundville is a town in Hale and Tuscaloosa counties in the U.S. state of Alabama. It was incorporated on December 22, 1908. From its incorporation until the 1970 census, it was wholly within Hale County. At the 2010 census the population was 2,427, up from 1,809 at the 2000 census. It is part of the Tuscaloosa Metropolitan Statistical Area. Within the town is Moundville Archaeological Site, the location of a prehistoric Mississippian culture political and ceremonial center.
Moundville is located in northern Hale County at 32°59′55″N 87°37′34″W (32.998521, -87.626006), on the south side of the Black Warrior River. The town limits extend north into Tuscaloosa County. Alabama State Route 69 passes through the east side of the town, leading north 16 miles (26 km) to Tuscaloosa and south 22 miles (35 km) to Greensboro, the Hale County seat.
According to the U.S. Census Bureau, Moundville has a total area of 4.6 square miles (12.0 km2), of which 0.06 square miles (0.15 km2), or 1.26%, are water.
At the 2000 census, there were 1,809 people, 809 total housing units with 688 being occupied households, and 479 families living in the town.