Myrtlewood is a town in Marengo County, Alabama, United States. At the 2010 census the population was 130, down from 139 in 2000.
A post office has been in operation at Myrtlewood since 1886. Myrtlewood was incorporated as a town in 1957. The town was named for a grove of crepe myrtle trees near the original town site.
Myrtlewood is located at 32°14′50″N 87°56′50″W (32.247254, -87.947141).
According to the U.S. Census Bureau, the town has a total area of 2.6 square miles (6.7 km2), all land.
As of the census of 2000, there were 139 people, 59 households, and 45 families residing in the town. The population density was 53.6 people per square mile (20.7/km2). There were 76 housing units at an average density of 29.3 per square mile (11.3/km2). The racial makeup of the town was 79.14% White and 20.86% Black or African American. 0.72% of the population were Hispanic or Latino of any race.