Odessa is a city in and the county seat of Ector County, Texas, United States. It is located primarily in Ector County, although a small section of the city extends into Midland County. Odessa's population was 99,940 at the 2010 census, making it the 28th-most populous city in Texas; estimates as of July 2019 indicate a population of 123,334 in the city. It is the principal city of the Odessa Metropolitan Statistical Area, which includes all of Ector County. The metropolitan area is also a component of the larger Midland–Odessa combined statistical area, which had a 2010 census population of 278,801; a recent report from the United States Census Bureau estimates that the combined population as of July 2015 is 320,513. In 2014, Forbes magazine ranked Odessa as the third-fastest growing small city in the United States. In 1948 Odessa was also the home of First Lady Barbara Bush, and the onetime home of former Presidents George H. W. Bush and George W. Bush. Former President George H.W. Bush has been quoted as saying "At Odessa we became Texans and proud of it."
Odessa is said to have been named after Odessa, Ukraine, because of the local shortgrass prairie's resemblance to Ukraine's steppe landscape.
Odessa was founded in 1881 as a water stop and cattle-shipping point on the Texas and Pacific Railway. The first post office opened in 1885. Odessa became the county seat of Ector County in 1891 when the county was first organized.