Owensville is a city in Gasconade County, Missouri, United States. The population was 2,676 at the 2010 census.
Owensville was named early merchant Frank Owens. According to local legend Owens and blacksmith Edward Luster decided on the name while playing horseshoes in 1847. According to one account Luster won the contest but thought Owensville sounded better than Lusterville. Another account said Owens won the contest. The first post office was in 1856 and the town was formally platted in 1886 with the arrival of the Chicago, Rock Island and Pacific Railroad.
According to the United States Census Bureau, the city has a total area of 2.64 square miles (6.84 km2), all land.
The city is approximately 70.8 miles southwest of St. Louis, 55.5 miles southeast of Jefferson City and 22.3 miles north of Cuba.
Missouri Highways 28 and 19 serve Owensville. In addition, the city is 22 miles north of Interstate 44.