Perham is a town in Aroostook County, Maine, United States. The population was 386 at the 2010 census. The town was named after Maine's 33rd governor, Sidney Perham.
According to the United States Census Bureau, the town has a total area of 36.64 square miles (94.90 km2), of which 36.53 square miles (94.61 km2) is land and 0.11 square miles (0.28 km2) is water.
At the 2010 census there were 386 people, 151 households, and 105 families living in the town. The population density was 10.6 inhabitants per square mile (4.1/km2). There were 190 housing units at an average density of 5.2 per square mile (2.0/km2). The racial makeup of the town was 97.4% White, 2.3% Native American, and 0.3% from two or more races. Of the 151 households 27.8% had children under the age of 18 living with them, 59.6% were married couples living together, 3.3% had a female householder with no husband present, 6.6% had a male householder with no wife present, and 30.5% were non-families. 23.8% of households were one person and 11.9% were one person aged 65 or older. The average household size was 2.56 and the average family size was 3.04.
The median age in the town was 45.3 years.