South Zanesville is a village in Muskingum County, Ohio, United States, along the Muskingum River at the mouth of Moxahala Creek. The population was 1,989 at the 2010 census.
South Zanesville is located at 39°54′9″N 82°1′12″W (39.902554, -82.019931).
According to the United States Census Bureau, the village has a total area of 0.83 square miles (2.15 km2), all land.
As of the census of 2010, there were 1,989 people, 830 households, and 539 families living in the village. The population density was 2,396.4 inhabitants per square mile (925.3/km2). There were 902 housing units at an average density of 1,086.7 per square mile (419.6/km2). The racial makeup of the village was 94.1% White, 3.0% African American, 0.3% Native American, 0.1% Asian, 0.1% Pacific Islander, 0.1% from other races, and 2.4% from two or more races. Hispanic or Latino of any race were 0.3% of the population.
There were 830 households, of which 34.9% had children under the age of 18 living with them, 39.0% were married couples living together, 18.4% had a female householder with no husband present, 7.5% had a male householder with no wife present, and 35.1% were non-families. 29.5% of all households were made up of individuals, and 12.1% had someone living alone who was 65 years of age or older. The average household size was 2.40 and the average family size was 2.90.