Yorkana is a borough in York County, Pennsylvania, United States. The population was 229 at the 2010 census. It is a linear town, spread along Mt. Pisgah Road which is called Main Street in town. The borough includes several dozen houses, two churches, and a few businesses.
Yorkana is located at 39°58′28″N 76°35′06″W.
According to the United States Census Bureau, the borough has a total area of 0.2 square miles (0.52 km2), all of it land.
As of the census of 2000, there were 239 people, 95 households, and 66 families residing in the borough. The population density was 1,306.9 people per square mile (512.7/km2). There were 100 housing units at an average density of 546.8 per square mile (214.5/km2). The racial makeup of the borough was 100.00% White.