Abiquiú (or Abiquiu (listen), Spanish pronunciation: [aβiˈkju], Tewa: Péshú:bú'; Northern Tiwa: Gultɨdda) is a small census-designated place located in Rio Arriba County, in northern New Mexico in the southwestern United States, about 53 miles (85 km) north of Santa Fe. Abiquiú's one school, an elementary school, is part of the Española Public Schools.
Abiquiú means "wild choke cherry place" in the Tewa language. The community is also called Santo Tomás de Abiquiú and the Pueblo of Santo Tomás de Abiquiú. Abiquiú was one of the homes of artist Georgia O'Keeffe from 1929 until 1984. The Georgia O'Keeffe Home and Studio is in Abiquiú and she also owned property at the nearby Ghost Ranch. Many of her paintings depict scenes near Abiquiú.
Abiquiú was first settled in 1742 by 24 Tewa Pueblo families led by a Roman Catholic priest, Francisco Delgado. The Tewa returned to New Mexico after a lengthy residence among the Hopi people in what would become Arizona. Their settlement in Abiquiú was part of the strategy by New Mexico to defend its frontiers against marauding American Indians such as the Apache, Comanche, and Navajo.