Alpine is a town in Lincoln County, Wyoming, United States. The population was 828 at the 2010 census.
Alpine is located at the southern end of the Snake River Canyon where the Snake River enters Palisades Reservoir. The town is also known as Alpine Junction since it marks the point where U.S. routes 26 and 89 turn in opposite directions. The two routes run concurrently through the Snake River Canyon from Jackson. In Alpine, Route 89 turns south toward Afton, while Route 26 turns north and follows the edge of Palisades Reservoir to Swan Valley, Idaho. Three rivers come together in the vicinity of Alpine: the Snake, the Salt, and the Greys - all three flow into the Palisades Reservoir, with the latter two giving up their waters to the Snake River.
According to the United States Census Bureau, the town has a total area of 0.70 square miles (1.81 km2), all land.
This climatic region is typified by large seasonal temperature differences, with warm to hot (and often humid) summers and cold (sometimes severely cold) winters. According to the Köppen Climate Classification system, Alpine has a humid continental climate, abbreviated "Dfb" on climate maps.
As of the census of 2010, there were 828 people, 346 households, and 221 families living in the town. The population density was 1,182.9 inhabitants per square mile (456.7/km2).