Blackstone is a town in Worcester County, Massachusetts, United States. The population was 9,026 at the 2010 census. It is a part of the Providence metropolitan area.
This region was first inhabited by the Nipmuc. Blackstone was settled by European immigrants in 1662 and was incorporated in 1845. The town was part of Mendon, Massachusetts, before becoming a separate municipality. Blackstone is within the area of the John H. Chaffee Blackstone River Valley National Heritage Corridor of Massachusetts and Rhode Island.
According to the United States Census Bureau, the town has a total area of 11.2 square miles (29 km2), of which 10.9 square miles (28 km2) is land and 0.3 square miles (0.78 km2), or 2.94%, is water. The Blackstone River, birthplace of the Industrial Revolution in the United States, meanders west to southeast, on the south border of town.
The town is bordered by North Smithfield, Rhode Island and Woonsocket, Rhode Island to the south; Millville, Massachusetts to the west; Mendon, Massachusetts to the north, and Bellingham, Massachusetts (Norfolk County) to the east.
Named places in the town include:
An East Blackstone railroad station used to be located in Bellingham.