Canistota is a city in McCook County, South Dakota, United States. The population was 656 at the 2010 census. Canistota is known for chiropractic services, especially the longstanding Ortman Clinic, which attracts many Amish people from around the Midwest.
Canistota was named after Canastota, New York, the home of a railroad official, but misspelled in the application for a post office. The city was platted in 1883. Its location is the northwest corner of Section 34, chosen by the Chicago Northwestern Railroad. Canistota incorporated in 1900.
Canistota is located at 43°35′51″N 97°17′36″W (43.597514, -97.293339).
According to the United States Census Bureau, the city has a total area of 0.56 square miles (1.45 km2), all of it land.
Canistota has been assigned the ZIP code 57012 and the FIPS place code 09300.
As of the census of 2010, there were 656 people, 242 households, and 159 families residing in the city. The population density was 1,171.4 inhabitants per square mile (452.3/km2). There were 281 housing units at an average density of 501.8 per square mile (193.7/km2). The racial makeup of the city was 95.0% White, 2.0% Native American, 0.5% Asian, 0.2% Pacific Islander, 0.9% from other races, and 1.5% from two or more races.