Centreville is a town in Amite and Wilkinson counties, Mississippi, United States. The population was 1,684 at the 2010 census. It is part of the McComb, Mississippi Micropolitan Statistical Area.
Bethany Presbyterian Church is a historic church in Centreville, built in 1855, and added to the National Register of Historic Places in 2003.
Centreville is located at 31°5′9″N 91°3′54″W (31.085909, -91.064922). The town is mostly within Wilkinson County with a portion in adjacent Amite County. In the 2000 census, 1,433 of the town's 1,680 residents (85.3%) lived in Wilkinson County and 247 (14.7%) in Amite County.
According to the United States Census Bureau, the town has a total area of 2.3 square miles (6.0 km2), all land.
As of the census of 2000, there were 1,680 people, 605 households, and 413 families residing in the town. The population density was 725.5 people per square mile (279.6/km2). There were 704 housing units at an average density of 304.0 per square mile (117.2/km2).