Cleona is a borough in Lebanon County, Pennsylvania, United States. It is part of the Lebanon, Pennsylvania Metropolitan Statistical Area. The population was 2,080 at the 2010 census.
Cleona is located at 40°20′14″N 76°28′29″W (40.337241, -76.474683).
According to the United States Census Bureau, the borough has a total area of 0.9 square miles (2.3 km2), all of it land.
Cleona is bordered to the north and east by North Lebanon Township (1.7 mi), to the south by North Cornwall Township (1.86 mi), and to the west by North Annville Township (0.37 mi) and Annville Township (0.47 mi).
As of the census of 2000, there were 2,148 people, 879 households, and 639 families residing in the borough. The population density was 2,464.9 people per square mile (953.3/km²). There were 913 housing units at an average density of 1,047.7 per square mile (405.2/km²). The racial makeup of the borough was 96.55% White, 1.02% African American, 0.05% Native American, 1.21% Asian, 0.05% Pacific Islander, 0.28% from other races, and 0.84% from two or more races. Hispanic or Latino of any race were 1.35% of the population.