Cottageville is a town in Colleton County, South Carolina, United States. The population was 762 at the 2010 census.
Cottageville is in eastern Colleton County, along U.S. Route 17 Alt. Walterboro, the county seat, is 11 miles (18 km) to the west, and Summerville is 20 miles (32 km) to the east.
According to the United States Census Bureau, Cottageville has a total area of 3.4 square miles (8.8 km2), all land.
As of the census of 2000, there were 707 people, 274 households, and 206 families residing in the town. The population density was 222.2 people per square mile (85.8/km2). There were 310 housing units at an average density of 97.4 per square mile (37.6/km2). The racial makeup of the town was 85.71% White, 11.88% African American, 0.42% Native American, 0.42% Asian, 0.14% Pacific Islander, 0.28% from other races, and 1.13% from two or more races. Hispanic or Latino of any race were 0.42% of the population.
There were 274 households, out of which 32.5% had children under the age of 18 living with them, 60.9% were married couples living together, 10.2% had a female householder with no husband present, and 24.8% were non-families. 21.5% of all households were made up of individuals, and 7.3% had someone living alone who was 65 years of age or older.