Estill is a town in Hampton County, South Carolina, United States. The population was 2,040 at the 2010 census.
Estill is located 52 miles (84 km) north of Savannah, Georgia, 64 miles (103 km) northwest of Hilton Head Island and 93 miles (150 km) west of Charleston. The major industries are timber and agriculture.
The town of Estill is located in the southern half of Hampton County. The town is named for Colonel John Holbrook Estill. Estill was formed in 1900 when the railroad, later Seaboard Air Line Railroad, needed a rail line between Augusta, Georgia and Savannah, Georgia. Upon construction of the rail line, the new town of Estill was incorporated in 1905.
The John Lawton House and Lawtonville Baptist Church are listed on the National Register of Historic Places.
Federal Correctional Institution, Estill is located near the town.
Main Article: 2020 Easter tornado outbreak
In the early morning hours of April 13, 2020, a large, violent EF4 Tornado struck areas just south of Estill.