Eunice is a city in Acadia and St. Landry parishes in the U.S. state of Louisiana. The 2010 census placed the population at 10,398, a decrease of 1,101, or 9.5 percent, from the 2000 tabulation of 11,499.
The St. Landry Parish portion of Eunice is part of the Opelousas–Eunice Micropolitan Statistical Area, while the Acadia Parish portion is part of the Crowley Micropolitan Statistical Area.
One-time lawman and pioneer land developer C.C. Duson is credited with founding Eunice, which was named for his second wife, Eunice Pharr Duson. He and his brother, W.W. Duson, had already founded Crowley, Louisiana in 1887, and now he looked to the north of the parish for future development. Duson bought 160 acres (0.65 km2) of land from Willie Humble of Prairie Faquetaïque and mapped out a town site, laid out in lots 50-by-140 feet, 12 lots to the block. Next, he persuaded the Southern Pacific Railroad to extend a branch line from Crowley to his new town. Then he began what he and his brother had learned how to do as well as anyone: promote land sales.