Garden City is a town in Clark County, South Dakota, United States. The population was 53 at the 2010 census.
Garden City was first settled in 1882, but it was in 1887 that Garden City was established as this was the year that the Chicago Milwaukee & St. Paul Railroad came through. The town was named from the site's garden-like setting.
Garden City is located at 44°57′28″N 97°34′47″W (44.957859, -97.579714).
According to the United States Census Bureau, the town has a total area of 0.40 square miles (1.04 km2), all land.
Garden City has been assigned the ZIP code 57236 and the FIPS place code 23460.
As of the census of 2010, there were 53 people, 21 households, and 17 families residing in the town. The population density was 132.5 inhabitants per square mile (51.2/km2). There were 35 housing units at an average density of 87.5 per square mile (33.8/km2). The racial makeup of the town was 94.3% White and 5.7% from two or more races. Hispanic or Latino of any race were 5.7% of the population.