Gilliam is a city in Saline County, Missouri, United States. The population was 197 at the 2010 census.
Gilliam was platted in 1878. The community was named after a local farmer and landowner, W. T. Gilliam. The Gilliam has been in operation since 1879.
Gilliam is located at 39°13′59″N 93°0′14″W (39.233168, -93.003890).
According to the United States Census Bureau, the city has a total area of 0.25 square miles (0.65 km2), all land.
As of the census of 2010, there were 197 people, 87 households, and 46 families living in the city. The population density was 788.0 inhabitants per square mile (304.2/km2). There were 101 housing units at an average density of 404.0 per square mile (156.0/km2). The racial makeup of the city was 95.9% White, 3.0% African American, 0.5% Native American, and 0.5% from two or more races. Hispanic or Latino of any race were 0.5% of the population.
There were 87 households, of which 28.7% had children under the age of 18 living with them, 39.1% were married couples living together, 9.2% had a female householder with no husband present, 4.6% had a male householder with no wife present, and 47.1% were non-families.