Glenwood is a city in, and the county seat of, Mills County, Iowa, United States. The population was 5,269 in the 2010 census, a decline from 5,358 in 2000.
Located in a hollow of the Loess Hills on the east side of the Missouri River, Glenwood was established by Mormons in 1848 as Coonsville. It prospered during the California Gold Rush largely due to the grain mill on Keg Creek. Coonsville was the scene of anti-Mormon mob violence. It became the county seat of Mills County in 1851. In 1852, after most Mormons left for Utah, it was renamed Glenwood after a Presbyterian minister, Glenn Wood.
The community supported the creation of Nebraska Territory in 1854. Two Glenwood attorneys were elected to the Nebraska territorial legislature, and they were run out of town for accepting shares in Scriptown. At the end of the Civil War, an Iowa Veteran's Orphans Home was founded here. The evangelist (and professional baseball athlete) Billy Sunday lived at the orphanage as a child.
The Burlington and Missouri River Railroad was completed through Glenwood in 1869. During the late 19th century, the community was widely known as Iowa's center of fruit production, particularly of apples, and it hosted an annual Apple Carnival.