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Holland is a city in Pemiscot County, Missouri, United States. The population was 229 at the 2010 census.
The first permanent settlement at Holland was made in 1871. The area experienced growth with the arrival of the St. Louis–San Francisco Railway in 1901. The town site was platted in 1902, and most likely was named after J. W. Holland, an early settler. A post office called Holland has been in operation since 1900.
Holland is located at 36°3′27″N 89°52′14″W (36.057399, -89.870467). The city lies a few miles west of the Mississippi River, and just north of the Missouri-Arkansas state line. U.S. Route 61 runs along Holland's southern boundary, connecting the city with Steele to the northeast and Blytheville, Arkansas, to the south. State Route E connects Holland with Cooter to the southeast.