Roanoke () is an independent city in the U.S. commonwealth of Virginia. At the 2010 census, the population was 97,032. It is located in the Roanoke Valley of the Roanoke Region of Virginia.
Roanoke is the largest municipality in Southwest Virginia, and is the principal municipality of the Roanoke Metropolitan Statistical Area (MSA), which had a 2010 population of 308,707. It is composed of the independent cities of Roanoke and Salem, and Botetourt, Craig, Franklin, and Roanoke counties. Bisected by the Roanoke River, Roanoke is the commercial and cultural hub of much of Southwest Virginia and portions of Southern West Virginia.
The town first called Big Lick was established in 1852 and chartered in 1874. It was named for a large outcropping of salt which drew the wildlife to the site near the Roanoke River. In 1882 it became the town of Roanoke, and in 1884 it was chartered as the independent city of Roanoke. The name Roanoke is said to have originated from an Algonquian word for "shell money". The name for the river was that used by the Algonquian speakers who lived 300 miles away where the river emptied into the sea near Roanoke Island. The native people who lived near where the city was founded did not speak Algonquian.