Killona is a census-designated place (CDP) in St. Charles Parish, Louisiana, United States. The population was 797 at the 2000 census.
Killona is located at 29°59′58″N 90°29′13″W (29.999471, -90.487081).
According to the United States Census Bureau, the CDP has a total area of 9.3 square miles (24 km2), of which 8.5 square miles (22 km2) is land and 0.9 square miles (2.3 km2) (9.13%) is water.
As of the census of 2000, there were 797 people, 252 households, and 191 families residing in the CDP. The population density was 94.1 people per square mile (36.3/km2). There were 284 housing units at an average density of 33.5 per square mile (12.9/km2). The racial makeup of the CDP was 7.40% White, 91.72% African American, 0.88% from other races. Hispanic or Latino of any race were 0.63% of the population.
There were 252 households, out of which 42.9% had children under the age of 18 living with them, 31.3% were married couples living together, 34.5% had a female householder with no husband present, and 24.2% were non-families. 19.8% of all households were made up of individuals, and 5.2% had someone living alone who was 65 years of age or older.