Louisville (pronounced LEW-iss-vill) is a city in Winston County, Mississippi. The population was 6,631 at the 2010 census. It is the county seat of Winston County.
Like Winston County, Louisville is named for Louis Winston (1784–1824), a colonel in the militia, a prominent lawyer, and a judge of the Mississippi Supreme Court. In 1863 Union Colonel Benjamin Grierson marched 900 troops through Louisville during his raid through Mississippi. There was no fighting in Winston County.
In 1927, a mob of 1,000 white men from Louisville, lynched two African-Americans, Jim and Mark Fox. The Foxes were accused of killing Clarence Nichols, a white man who started a fight with them because they would not let him pass their Ford touring car in his Chevrolet.
On April 28, 2014, Louisville was hit by an EF4 tornado, which killed 10 people.
Louisville is located at 33°7′23″N 89°3′22″W (33.122931, -89.056182). According to the United States Census Bureau, the city has a total area of 15.3 square miles (40 km2), of which 15.1 square miles (39 km2) is land and 0.2 square miles (0.52 km2) (1.44%) is water. It is known by many as the "Front porch of the South".
As of the census of 2000, there were 7,006 people, 2,641 households, and 1,817 families living in the city. The population density was 464.5 people per square mile (179.4/km2).