Orono () is a town in Penobscot County, Maine, United States. Located on the Penobscot and Stillwater rivers, it was first settled by British-American colonists in 1774. They named it in honor of Chief Joseph Orono, a sachem of the indigenous Penobscot nation who long occupied this territory.
In the nineteenth century, the town became a center of the lumber industry. Sawmills on the rivers were powered by the water, and logs were floated downriver on the Penobscot for shipping and export from coastal ports.
Since 1865 it has been the location of the University of Maine, established as a land-grant institution and the state's flagship educational institution. In the fall of 2018, the university enrolled 11,404 students at Orono. Not including university residents, the town's population was 10,362 at the 2010 census.
According to the United States Census Bureau, the town has a total area of 19.60 square miles (50.76 km2), of which, 18.19 square miles (47.11 km2) of it is land and 1.41 square miles (3.65 km2) is water. The town is divided by the Stillwater River, a branch of the Penobscot River.