Ruther Glen is an unincorporated community in Caroline County, Virginia, located near the interchange between Interstate 95 and Virginia State Highway 207, at 37°56′19.6152″N 77°28′17.2776″W (37.938782, -77.471466).
It is approximately 30 miles (48 km) north of Richmond. Mattaponi Springs golf course is located in the community. Numerous telemarketing organizations use phone number masking techniques to make "Ruther Glen, Virginia" appear on prospects' caller ID units.
Politician Julian M. Quarles was born near the community.
Caroline County's only private Christian school, The Carmel School, is located in Ruther Glen. The community is also where Atlantic Union Bank is headquartered.