Spofford is a city in Kinney County, Texas, United States. The population was 95 at the 2010 census.
Spofford is located in southern Kinney County at 29°10′22″N 100°24′41″W (29.172681, -100.411388). It is on the east side of Texas State Highway 131, which leads north 10 miles (16 km) to Brackettville, the county seat, and south 24 miles (39 km) to U.S. Route 277 in the Rio Grande valley.
According to the United States Census Bureau, Spofford has a total area of 0.2 square miles (0.6 km2), all of it land.
As of the census of 2000, 75 people, 24 households, and 19 families resided in the city. The population density was 298.8 people per square mile (115.8/km2). The 38 housing units averaged 151.4/sq mi (58.7/km2). The racial makeup of the city was 81.33% White, 18.67% fromother races. Hispanics or Latinos of any race were 52.00% of the population.
Of the 24 households, 50.0% had children under the age of 18 living with them, 66.7% were married couples living together, 8.3% had a female householder with no husband present, and 16.7% were not families. About 16.7% of all households were made up of individuals, and 16.7% had someone living alone who was 65 years of age or older.