Spokane ( (listen) spoh-KAN) is a city in and the county seat of Spokane County, Washington, United States. It is in eastern Washington along the Spokane River adjacent to the Selkirk Mountains and west of the Rocky Mountain foothills, 92 miles (148 km) south of the Canada–U.S. border, 18 miles (30 km) west of the Washington–Idaho border, and 279 miles (449 km) east of Seattle along Interstate 90.
Spokane is the economic and cultural center of the Spokane metropolitan area, the Spokane–Coeur d'Alene combined statistical area, and the Inland Northwest. It is known as the birthplace of Father's Day, and its official nickname is the "Lilac City". A pink double flower cultivar of the common lilac, known as Syringa vulgaris 'Spokane', is named for the city. The city and the wider Inland Northwest area are served by Spokane International Airport, 5 miles (8 km) west of downtown Spokane. According to the 2010 Census, Spokane had a population of 208,916, making it the second-largest city in Washington, and the 100th-largest city in the United States. In 2019, the United States Census Bureau estimated the city's population at 222,081 and the population of the Spokane Metropolitan Area at 573,493.
The first people to live in the area, the Spokane tribe (their name meaning "children of the sun" in Salishan), lived off plentiful game. David Thompson explored the area with the westward expansion and establishment of the North West Company's Spokane House in 1810. This trading post was the first long-term European settlement in Washington.