Thayne is a town in Lincoln County, Wyoming, United States. The population was 366 at the 2010 census.
Thayne is located at 42°55′11″N 111°0′3″W (42.919754, -111.000714), at 5906 feet in elevation. It sits in the northern portion of Wyoming's grassy Star Valley, close to the Salt River. Thayne is surrounded by green grassland and ranches, with forested mountains at the valley's edge.
According to the United States Census Bureau, the town has a total area of 1.39 square miles (3.60 km2), all land.
As of the census of 2010, there were 366 people, 144 households, and 90 families living in the town. The population density was 263.3 inhabitants per square mile (101.7/km2). There were 171 housing units at an average density of 123.0 per square mile (47.5/km2). The racial makeup of the town was 91.5% White, 1.1% Asian, 6.0% from other races, and 1.4% from two or more races. Hispanic or Latino of any race were 9.3% of the population.