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Tice is an unincorporated community and census-designated place (CDP) in Lee County, Florida, United States. As of the 2010 census, the CDP population was 4,470. It is part of the Cape Coral-Fort Myers, Florida Metropolitan Statistical Area.
Tice is in north-central Lee County at 26°40′29″N 81°49′3″W (26.674815, -81.817565). It is bordered to the south and west by the city of Fort Myers, the county seat. Its northern edge is the Caloosahatchee River.
Florida State Road 80 (Palm Beach Boulevard) is the main road through the community, leading northeast 1 mile (1.6 km) to Interstate 75 and southwest 4 miles (6 km) to the center of Fort Myers. Going farther east, SR 80 leads 25 miles (40 km) to LaBelle and 57 miles (92 km) to Clewiston near Lake Okeechobee.
According to the United States Census Bureau, the Tice CDP has a total area of 1.2 square miles (3.2 km2), of which 1.1 square miles (2.8 km2) are land and 0.2 square miles (0.4 km2), or 12.31%, are water.
As of the census of 2000, there were 4,538 people, 1,556 households, and 1,026 families residing in the CDP. The population density was 3,979.3 people per square mile (1,537.0/km²). There were 1,789 housing units at an average density of 1,568.7/sq mi (605.9/km²).