Wood River is a city in Madison County, Illinois, United States. The population was 10,657 according to the 2010 census.
Wood River is located at 38°51′47″N 90°5′19″W (38.863047, -90.088527).
According to the 2010 census, Wood River has a total area of 7.154 square miles (18.53 km2), of which 6.98 square miles (18.08 km2) (or 97.57%) is land and 0.174 square miles (0.45 km2) (or 2.43%) is water.
Wood River is located on the Mississippi River approximately 15 miles (24 km) upstream of downtown St. Louis, Missouri, among several contiguous cities and villages that have come to be known as the "Riverbend" area. The current confluence of the Mississippi and the Missouri rivers is just south of one of these neighboring villages, Hartford. Other cities making up the "Riverbend" include Alton, East Alton, Godfrey, Roxana and Bethalto.
At the 2000 census there were 11,296 people, 4,725 households, and 2,995 families living in the city. The population density was 1,865.2 people per square mile (719.7/km²). There were 5,001 housing units at an average density of 825.8 per square mile (318.6/km²). The racial makeup of the city was 97.57% White, 0.63% African American, 0.27% Native American, 0.45% Asian, 0.35% from other races, and 0.73% from two or more races.