Baldwyn is a city located in Lee and Prentiss counties, Mississippi, located in the northern part of the Tupelo micropolitan area. The population was 3,297 at the 2010 census.
Located five miles north of Guntown, the main street of Baldwyn runs along the county line of Lee and Prentiss counties. The city has the unusual distinction of having been incorporated in four counties. It was incorporated by an Act of the Legislature in Tishomingo and Itawamba counties on April 1, 1861. Tishomingo County was divided into Alcorn, Prentiss and Tishomingo in 1870, while Lee County was formed from parts of Itawamba and Pontotoc counties in 1866.
Baldwyn is an outgrowth of the village of Carrollville: when the Mobile and Ohio Railroad was being built during the years of 1848 to 1861, it missed Carrollville by one and one-half miles and the citizens moved to the new town of Baldwyn, which was named for the civil engineer who surveyed the road through the town. Tishomingo, chief of the Chickasaw, lived at old Carrollville but died at Little Rock, Arkansas, in 1839 of smallpox while being moved west with his tribe.
The population of Baldwyn was 3,304 in 2017.
In the 2000 census, 1,892 of the city's 3,321 residents (57.0%) lived in Prentiss County and 1,429 (43.0%) in Lee County. According to the United States Census Bureau, the city has a total area of 11.6 square miles (30.0 km2), of which 11.5 square miles (29.9 km2) is land and 0.1 square mile (0.1 km2) (0.43%) is water.
As of the census of 2000, there were 3,321 people, 1,331 households, and 886 families residing in the city. The population density was 287.9 sq mi). There were 1,472 housing units at an average density of 127.6 per square mile. The racial makeup of the city was 54.53% White, 43.87% African American, 0.24% Native American, 0.30% from other races, and 1.05% from two or more races.