Bertrand is a city in Mississippi County, Missouri, United States. The population was 821 at the 2010 census.
Bertrand was platted in 1859. The community has the name of one Mr. Bertrand, a railroad promoter. A post office called Bertrand has been in operation since 1874.
Bertrand is located at 36°54′37″N 89°26′54″W (36.910323, -89.448213). According to the United States Census Bureau, the city has a total area of 0.78 square miles (2.02 km2), all land.
As of the census of 2010, there were 821 people, 341 households, and 232 families living in the city. The population density was 1,052.6 inhabitants per square mile (406.4/km2). There were 355 housing units at an average density of 455.1 per square mile (175.7/km2). The racial makeup of the city was 97.32% White, 1.83% Black or African American, 0.12% Native American, 0.12% Asian, 0.12% from other races, and 0.49% from two or more races.