Brunson is a town in Hampton County, South Carolina, United States. The population was 554 at the 2010 census.
Brunson is located in northern Hampton County at 32°55′36″N 81°11′16″W (32.926738, -81.187651). U.S. Route 278 (Railroad Avenue) passes through the center of town, leading northwest 3 miles (5 km) to Fairfax and southeast 6 miles (10 km) to Hampton, the county seat.
According to the United States Census Bureau, the town of Brunson has a total area of 1.0 square mile (2.6 km2), all land.
As of the census of 2000, there were 589 people, 237 households, and 162 families residing in the town. The population density was 581.3 people per square mile (225.2/km2). There were 287 housing units at an average density of 283.3 per square mile (109.7/km2). The racial makeup of the town was 55.35% White, 42.44% African American, 1.36% from other races, and 0.85% from two or more races. Hispanic or Latino of any race were 1.53% of the population.
There were 237 households, out of which 30.8% had children under the age of 18 living with them, 46.8% were married couples living together, 17.3% had a female householder with no husband present, and 31.6% were non-families. 28.3% of all households were made up of individuals, and 13.9% had someone living alone who was 65 years of age or older.