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Sycamore is a town in Allendale County, South Carolina, United States. The population was 180 as of the 2010 census.
Sycamore is located at 33°2′19″N 81°13′19″W (33.038490, -81.222032).
According to the United States Census Bureau, the town has a total area of 3.2 square miles (8.2 km2), of which 0.008 square miles (0.02 km2), or 0.29%, is water.
At the 2000 census there were 185 people, 81 households, and 54 families living in the town. The population density was 58.3 people per square mile (22.5/km2). There were 93 housing units at an average density of 29.3 per square mile (11.3/km2). The racial makeup of the town was 61.62% White, 35.14% African American, 0.54% Native American, 0.54% from other races, and 2.16% from two or more races. Hispanic or Latino of any race were 2.16%.
Of the 81 households 22.2% had children under the age of 18 living with them, 48.1% were married couples living together, 13.6% had a female householder with no husband present, and 33.3% were non-families. 29.6% of households were one person and 16.0% were one person aged 65 or older. The average household size was 2.28 and the average family size was 2.85.
The age distribution was 18.9% under the age of 18, 8.1% from 18 to 24, 25.9% from 25 to 44, 25.4% from 45 to 64, and 21.6% 65 or older. The median age was 43 years.