Menno is a city in Hutchinson County, South Dakota, United States. The population was 608 at the 2010 census.
Menno was laid out in 1879.
Menno is located at 43°14′16″N 97°34′39″W (43.237840, -97.577440).
According to the United States Census Bureau, the city has a total area of 0.52 square miles (1.35 km2), all land.
Menno has been assigned the ZIP code 57045 and the FIPS place code 41980.
As of the census of 2010, there were 608 people, 285 households, and 173 families residing in the city. The population density was 1,169.2 inhabitants per square mile (451.4/km2). There were 327 housing units at an average density of 628.8 per square mile (242.8/km2). The racial makeup of the city was 98.7% White, 0.5% Native American, and 0.8% from two or more races. Hispanic or Latino of any race were 0.8% of the population.
There were 285 households, of which 17.5% had children under the age of 18 living with them, 54.4% were married couples living together, 4.2% had a female householder with no husband present, 2.1% had a male householder with no wife present, and 39.3% were non-families. 37.2% of all households were made up of individuals, and 21.4% had someone living alone who was 65 years of age or older.