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Republic is an unincorporated community and census-designated place (CDP) in Fayette County, Pennsylvania, United States. The population was 1,096 at the 2010 census, down from 1,396 at the 2000 census. The community is in Redstone Township.
Republic is located in western Fayette County at 39°57′56″N 79°52′41″W (39.965531, -79.878064), on the western edge of Redstone Township. It is bordered to the west across Dunlap Creek by Luzerne Township.
Pennsylvania Route 166 passes through Republic, leading north 5 miles (8 km) to Brownsville and south 6 miles (10 km) to Edenborn. Pennsylvania Route 43, the Mon–Fayette Expressway, passes 3 miles (5 km) north of Republic, with access from Exit 22.
According to the United States Census Bureau, the CDP has a total area of 0.73 square miles (1.9 km2), all of it land.
As of the census of 2000, there were 1,396 people, 614 households, and 359 families residing in the CDP. The population density was 1,887.4 people per square mile (728.4/km2). There were 714 housing units at an average density of 965.3/sq mi (372.5/km2). The racial makeup of the CDP was 90.47% White, 7.02% African American, 0.29% Native American, 0.36% from other races, and 1.86% from two or more races.