Shirley is a town in northeast Van Buren County, Arkansas, United States, along the Middle Fork of the Little Red River. A one-time railroad outpost, the community today is oriented toward agriculture and recreational activities due to the river and Greers Ferry Lake. The population was 223 at the 2010 census.
Shirley is located at 35°39′21″N 92°19′0″W (35.655936, -92.316554).
According to the United States Census Bureau, the town has a total area of 2.5 square miles (6.5 km2), of which 2.4 square miles (6.2 km2) is land and 0.1 square miles (0.26 km2) (2.85%) is water.
As of the census of 2010, there were 223 people, 136 households, and 91 families residing in the town. The population density was 140.9 inhabitants per square mile (54.4/km2). There were 132 housing units at an average density of 71.9 per square mile (27.8/km2). The racial makeup of the town was 96.14% White, 0.89% Black or African American, 1.89% Native American, and 2.08% from two or more races. 1.19% of the population were Hispanic or Latino of any race.
There were 132 households, out of which 33.1% had children under the age of 18 living with them, 58.8% were married couples living together, 6.6% had a female householder with no husband present, and 32.4% were non-families.