West Memphis is the largest city in Crittenden County, Arkansas, United States. The population was 26,245 at the 2010 census, ranking it as the state's 18th largest city, behind Bella Vista. It is part of the Memphis metropolitan area, and is located directly across the Mississippi River from Memphis, Tennessee.
Native Americans lived in the Mississippi River Valley for at least 10,000 years, although much of the evidence of their presence has been buried or destroyed. The Indians of the Mississippian Period were the last native inhabitants of the West Memphis area. Mound City Road, located within the eastern portion of the West Memphis city limits, has a marker indicating that the villages of Aquixo (Aquijo) or Pacaha were in the area. Several mounds are still visible.
Explorers from both Spain and France visited the area near West Memphis. Among those explorers were Hernando de Soto and his men from Spain and Father Jacques Marquette and Louis Jolliet from France. By the time French hunters and explorers entered the region, the Mississippian towns and other settlements had been abandoned.